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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN1 All Species: 27.27
Human Site: T157 Identified Species: 46.15
UniProt: Q16512 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16512 NP_002732.3 942 103932 T157 Q T Y S N G S T K D R K L L L
Chimpanzee Pan troglodytes XP_512443 1169 127241 T384 Q T Y S N G S T K D R K L L L
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 P249 H T C A S G T P K E R K L L A
Dog Lupus familis XP_542019 1076 118222 T290 Q T Y S N G S T K D R K L L L
Cat Felis silvestris
Mouse Mus musculus P70268 946 104392 S157 Q T Y S N G S S K D R K L L L
Rat Rattus norvegicus Q63433 946 104449 T157 Q T Y S N G S T K D R K L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 P236 Q M Y A N G T P K E R K L V A
Chicken Gallus gallus XP_422357 1013 114806 S194 Q M Y S N G S S K D R K L L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689331 948 107057 T175 P I Y T N G S T K D K K M L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 T58 K T Q V R P K T N E P R W N E
Sea Urchin Strong. purpuratus XP_787090 799 90414 D110 V E A S H K L D I L R E G L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 D147 L T K L Y Q I D G D Q R S S S
Red Bread Mold Neurospora crassa P87253 1142 127954 D192 Q L Y Q M E G D K K S K L D A
Conservation
Percent
Protein Identity: 100 79.3 38.7 83 N.A. 91.6 91.9 N.A. 42.2 57.6 N.A. 66.7 N.A. 29 N.A. 27.8 48.5
Protein Similarity: 100 79.9 52.6 84.3 N.A. 94.7 94.6 N.A. 56.1 72.1 N.A. 79.5 N.A. 42.8 N.A. 43.4 61.7
P-Site Identity: 100 100 46.6 100 N.A. 93.3 100 N.A. 53.3 80 N.A. 60 N.A. 0 N.A. 13.3 20
P-Site Similarity: 100 100 73.3 100 N.A. 100 100 N.A. 80 86.6 N.A. 80 N.A. 0 N.A. 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 28.3
Protein Similarity: N.A. N.A. N.A. N.A. 44.4 45.1
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 15 0 0 0 0 0 0 0 0 0 0 29 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 22 0 58 0 0 0 8 0 % D
% Glu: 0 8 0 0 0 8 0 0 0 22 0 8 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 65 8 0 8 0 0 0 8 0 0 % G
% His: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 0 8 0 0 0 0 0 0 % I
% Lys: 8 0 8 0 0 8 8 0 72 8 8 72 0 0 0 % K
% Leu: 8 8 0 8 0 0 8 0 0 8 0 0 65 65 36 % L
% Met: 0 15 0 0 8 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 58 0 0 0 8 0 0 0 0 8 0 % N
% Pro: 8 0 0 0 0 8 0 15 0 0 8 0 0 0 0 % P
% Gln: 58 0 8 8 0 8 0 0 0 0 8 0 0 0 8 % Q
% Arg: 0 0 0 0 8 0 0 0 0 0 65 15 0 0 0 % R
% Ser: 0 0 0 50 8 0 50 15 0 0 8 0 8 8 8 % S
% Thr: 0 58 0 8 0 0 15 43 0 0 0 0 0 0 0 % T
% Val: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 65 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _